Mikhailova, ValentinaTartu Ülikool. Loodus- ja täppisteaduste valdkondTartu Ülikool. Tehnoloogiainstituut2021-07-012021-07-012021http://hdl.handle.net/10062/72918The cell cycle of Saccharomyces cerevisiae is governed by cyclin dependent kinases (Cdks), which are activated by periodically synthesized and degraded cyclins. The substrate target-ing by a cyclin-Cdk complex is mediated by the active site on the Cdk and the cyclin docking pocket. Docking interactions between short linear motifs (SLiMs) in target proteins and cy-clin-dependent kinases are shown to be critical regulators of different cell cycle events. SLiMs function in almost every pathway due to their role in regulatory function and signal transduction.engembargoedAccessAttribution-NonCommercial-NoDerivatives 4.0 InternationalBudding yeastcell cycleCdkClb5SLiMSld2magistritöödThesis