Reisberg, Sulev, juhendajaJääger, Kersti, juhendajaOrula, Ida MariaTartu Ülikool. Loodus- ja täppisteaduste valdkondTartu Ülikool. Arvutiteaduse instituut2023-09-212023-09-212021https://hdl.handle.net/10062/92341Pharmacogenetics is a branch of personalised medicine that investigates the impact of genetic fac-tors on drug response. Adequate IT solutions are the key components of applying pharmacogenetic knowledge to clinical practice. This thesis describes the process of designing and implementing a curated scientific knowledge base to be used by a software-based medical device for pharmaco-genetic testing. Based on scientific literature, a prototype is built to identify main domain objects and processes for curating the knowledge base. The final implementation is created by using the Qure Data Management Platform.engopenAccessAttribution-NonCommercial-NoDerivatives 4.0 InternationalKnowledge basepharmacogeneticsdata curationmagistritöödinformaatikainfotehnoloogiainformaticsinfotechnologyThesis