Kurg, Reet, juhendajaNesterovich, AlexeyTartu Ülikool. Loodus- ja täppisteaduste valdkondTartu Ülikool. Tehnoloogiainstituut2024-06-182024-06-182024https://hdl.handle.net/10062/99919Showing common features of tumorigenesis, Melanoma-associated antigen A10 (MAGEA10) possesses the potential for cancer therapy. MAGEA10 is a highly immunogenic MAGEA family member that acts as a hub protein and is associated with global hypomethylation. The N-terminus of MAGEA10 is involved in its expression, nuclear transport, and electrophoretic mobility shift. This thesis aims to characterise further the N-terminus of MAGEA10 and find its potential interaction partners.enAttribution-NonCommercial-NoDerivs 3.0 EstoniaTumorigenesisMelanoma-associated antigenN-terminusProtein-protein interactionmagistritöödThe N-terminus of Melanoma-associated antigen A10 interacts with peripheral nucleoporinsMelanoomi-seoselise antigeeni A10 N-terminaalne ots interakteerub perifeersete tuumapoori valkudegaThesis