Lineaarne mudel geeni ekspressiooni andmete analüüsi jaoks
| dc.contributor.advisor | Vilo, Jaak | et |
| dc.contributor.author | Tretjakov, Konstantin | et |
| dc.contributor.other | Tartu Ülikool. Matemaatika-informaatikateaduskond | et |
| dc.contributor.other | Tartu Ülikool. Arvutiteaduse instituut | et |
| dc.date.accessioned | 2013-09-09T08:38:34Z | |
| dc.date.available | 2013-09-09T08:38:34Z | |
| dc.date.issued | 2005 | et |
| dc.description.abstract | The thesis proposes a novel method for the analysis of microarray data based on fitting a specific linear model that combines microarray data with DNA sequence information. The model is both descriptive and predictive: its coefficients provide insight into the structure of the genetic regulatory networks, and its predictive performance may be used to find a set of genes that play important role in transcription regulation (transcription factors). An efficient algorithm is proposed for calculating the least-squares fit for the parameters of the model. The proposed method is tested on a synthetic dataset and the results indicate that the approach is capable of detecting interesting relations in the data. | et |
| dc.identifier.uri | http://hdl.handle.net/10062/32923 | |
| dc.language.iso | en | et |
| dc.publisher | Tartu Ülikool | et |
| dc.subject.other | bakalaureusetööd | et |
| dc.subject.other | informaatika | et |
| dc.subject.other | infotehnoloogia | et |
| dc.subject.other | informatics | en |
| dc.subject.other | infotechnology | en |
| dc.title | Lineaarne mudel geeni ekspressiooni andmete analüüsi jaoks | et |
| dc.title.alternative | A Linear Model of Genetic Transcription Regulation that Combines Microarray and Genome Sequence Data | et |
| dc.type | Thesis | et |
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