Bioinseneeria instituut

Selle valdkonna püsiv URIhttps://hdl.handle.net/10062/99556

Sirvi

Sirvi Bioinseneeria instituut Autor "Enkvist, Erki, juhendaja" järgi

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    The Effect of Distant Structural Fragments on Long Lifetime Photoluminescence Properties of ARC-Lum Probes
    (Tartu Ülikool, 2025) Enageli, Lizi; Enkvist, Erki, juhendaja; Viht, Kaido, juhendaja; Tartu Ülikool. Loodus- ja täppisteaduste valdkond; Tartu Ülikool. Bioinseneeria instituut
    Previously discovered bisubstrate inhibitors exhibit room-temperature phosphorescence when complexed with protein kinase CK2. Such compounds can serve as valuable probes for studying protein kinases in the cell lysates and other biologically derived samples. In the present work, the effect of structural fragments distant from the phosphorescent moieties on the photoluminescence properties of the probes is investigated. Additionally, the influence of oxygen removal on photoluminescence is characterized. The findings of this work contribute to the design of novel, bright probes for CK2.