Sirvi Autor "Kaup, Karl Kristjan, juhendaja" järgi

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Comparison of psychedelic mixed reality experiences - an explorative study
(Tartu Ülikool, 2024) Kaljo, Madli; Aru, Jaan, juhendaja; Kaup, Karl Kristjan, juhendaja; Vasser, Madis, juhendaja; Tartu Ülikool. Sotsiaalteaduste valdkond; Tartu Ülikool. Psühholoogia instituut
The aim of this study was to investigate various psychedelic virtual (VR) and augmented reality (AR) experiences and compare perceived psychedelic effects they produced. A total of 24 participants (N=24) were exposed to 12 different experiences, including three VR, eight AR, and one baseline (AR) experience. Following each encounter, participants responded to a brief custom-made questionnaire assessing both psychedelic and affective dimensions of the experience. Mixed measures ANOVA revealed that six experiences, comprising three VR and three AR, exhibited significant differences from the baseline measure in terms of psychedelic effects. While VR experiences generally yielded higher results than AR experiences, not all of them differ significantly from three higher scoring AR experiences. SAM affective dimensions correlated significantly with overall psychedelic effect, correlation was weak to medium.
Effects of LSD, DMT and psilocybin on cognitive and psychological functions: a systematic review of the literature
(Tartu Ülikool, 2025) Kase, Marten; Aru, Jaan, juhendaja; Kaup, Karl Kristjan, juhendaja; Tartu Ülikool. Sotsiaalteaduste valdkond; Tartu Ülikool. Psühholoogia instituut
Objective: To carry out a systematic review of modern-era (1990-2025) placebo-controlled studies assessing the acute and post-acute effects of LSD, DMT and psilocybin on cognitive and psychological functions. Method: From February 28 to March 19, 2025, PubMed and APA PsychINFO were systematically searched for placebo-controlled studies examining how psychedelics influence empathy, reaction time, emotional processing, memory, cognitive flexibility and related cognitive functions. Additional searches were done in Google Scholar. Results: The systematic review included 30 studies. Psychedelics tended to enhance emotional empathy, but had no effect on cognitive empathy. Psychedelics impaired, enhanced or had no effect on memory depending on the task and timing of the assessment. Dose-dependent impairments were seen in many of the reaction time tasks, although some studies found no effects. Some studies found impaired recognition of negative stimuli under the acute effects of psychedelics. The findings regarding cognitive flexibility were mixed. Limitations: Many studies had small samples and it is hard to find a reliable placebo due to psychedelics’ unique subjective effects. Future studies should use bigger samples and also study more longitudinal effects of psychedelics on cognitive and psychological functions.
Exploring Entropy and Signal Diversity in Neural Networks Using the AdEx Model
(Tartu Ülikool, 2025) Hubel, Ares; Kaup, Karl Kristjan, juhendaja; Tartu Ülikool. Loodus- ja täppisteaduste valdkond; Tartu Ülikool. Arvutiteaduse instituut
The intricate activity of neural systems presents a significant frontier in scientific understanding. This master's thesis delves into this complexity by computationally investigating entropy and signal diversity, which are key metrics for characterizing information processing in the brain. Employing Adaptive Exponential Integrate-and-Fire (AdEx) neural network models, the research systematically explores how fundamental neuronal and network parameters, including synaptic delay, weight, and connectivity patterns, influence the dynamic behavior of these networks. This investigation also aims to deepen the understanding of the AdEx model's operational characteristics under varied conditions. The study quantifies these influences through Shannon Entropy (SE) of spike train activity and Lempel-Ziv Complexity (LZC) derived from spike train patterns. The overarching goals are to clarify the mechanisms by which specific parameters govern signal richness, to further elucidate the workings of the AdEx model, and to assess the implications of the findings for theories like the Entropic Brain Hypothesis.
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(Tartu Ülikool, 2017) Kaup, Karl Kristjan, juhendaja; Kiisk, Madis, juhendaja; Tartu Ülikool. Loodus- ja täppisteaduste valdkond; Tartu Ülikool. Füüsika instituut