ADA :: sirvimine Kuupäev järgi

Kirje

Sügiskuu lõppes lausa suviselt

(Maaleht, 2007-10-04) Kallis, A.

Kirje

KnowARC Information System

(2007-10-04T07:00:17Z) Nazarov, Aleksei

Kirje

Söömishäirete riskifaktorite esinemine Eesti aeroobikatreenerite seas

(2007-10-04T07:05:58Z) Parm, Anna-Liisa

Kirje

Autoimmune diabetes: an immunological study of type 1 diabetes in humans and in a model of experimental diabetes (in RIP-B7.1 mice)

(2007-10-04T07:11:39Z) Rajasalu, Tarvo

In the clinical part of the study the prevalence of genetic markers and disease-associated autoantibodies in Estonian patients with new-onset type 1 diabetes were determined, and the associations between genetic factors and autoantibodies were analysed. The experimental part of the study was carried out in RIP(rat insulin promoter)-B7.1 transgenic mice in whom the expression of the immunostimulatory B7.1 molecule in -cells increases the susceptibility of the mice to autoimmune diabetes. In the current study the main diabetogenic T cell population of this experimental model was characterised and the target epitope of the pathogenic T cell response against the insulin molecule was identified.