Characterization of gut microbiome composition in T2D patients under SGLT2i and GLP1RA treatment
Date
2023
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Tartu Ülikool
Abstract
Type 2 Diabetes (T2D) is a globally recognized health concern that has garnered significant
research attention. This thesis work focuses on gut microbiome analysis in T2D patients who
start taking two medications antidiabetic drugs: Empaglifrozin (SGLT2i) and Semaglutide
(GLP1RA). Microbiome composition was analyzed using 16S rRNA sequencing. The research
aims to enhance our understanding of how the gut microbiome is related to
SGLT2/GLP1 drug intake, potentially leading to the development of personalized treatment
approaches for improved patient outcomes.
Description
Keywords
Type 2 Diabetes, SGLT2i, GLP1RA, gut microbiome, Empaglifrozin, Semaglutide