Driving risks of young drivers with symptoms of attention deficit hyperactivity disorder: association with the dopamine transporter gene VNTR polymorphism
| dc.contributor.author | Tokko, Tõnis | |
| dc.contributor.author | Eensoo, Diva | |
| dc.contributor.author | Miškinyte, Grete | |
| dc.contributor.author | Harro, Jaanus | |
| dc.date.accessioned | 2023-02-21T13:17:42Z | |
| dc.date.available | 2023-02-21T13:17:42Z | |
| dc.date.issued | 2022 | |
| dc.description.abstract | Road traffic injuries are a leading cause of death for young adults, and young drivers with higher expression of symptoms of attention deficit-hyperactivity disorder (ADHD) could pose an even greater risk in traffic. Dopaminergic dysfunction has been found to occur in ADHD, with the dopamine transporter (DAT) gene VNTR polymorphism (DAT1 VNTR; rs28363170) being one of the most consistent genetic markers. Thus, we aimed at clarifying how the ADHD symptoms and the DAT1 VNTR relate to risk-taking behaviour in traffic, impulsivity and driving anger in young drivers. We used data of two traffic behaviour study samples (n = 741, mean age = 23.3±7.2 years; n = 995, mean age = 22.9±8.1 years) and the Estonian Children Personality Behaviour and Health Study (ECPBHS; traffic behaviour data n = 1016, mean age = 25.2±2.1 years). ADHD symptoms were assessed by self-report with the Adult ADHD Self-Report Scale (ASRS v1.1) and impulsivity with the Adaptive and Maladaptive Impulsivity Scale. Traffic behavioural measures were either self-reported (Driver Behaviour Questionnaire, Driving Anger Scale) or obtained from databases (registered accidents and violations). Drivers with more self-reported ADHD symptoms also reported more risk-taking in traffic and had more of recorded traffic accidents and violations. DAT1 9R carriers had a higher probability of high traffic risk behaviour only if they also had ADHD symptoms. Conclusion Higher level of ADHD symptoms is a significant risk factor in traffic, and carrying of the DAT1 9R allele appears to aggravate these risks. | et |
| dc.identifier.uri | https://doi.org/10.1080/08039488.2022.2032330 | |
| dc.identifier.uri | http://hdl.handle.net/10062/89268 | |
| dc.language.iso | eng | et |
| dc.relation | info:eu-repo/grantAgreement/EC/H2020/728018///Eat2beNICE | et |
| dc.relation | info:eu-repo/grantAgreement/EC/H2020/667302///CoCA | |
| dc.relation.ispartofseries | Nordic Journal of Psychiatry;Volume 76, 2022 - Issue 8 | |
| dc.rights | info:eu-repo/semantics/openAccess | et |
| dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 International | * |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
| dc.subject | ADHD | en |
| dc.subject | DAT1 VNTR | en |
| dc.subject | traffic behaviour | en |
| dc.subject | impulsivity | en |
| dc.title | Driving risks of young drivers with symptoms of attention deficit hyperactivity disorder: association with the dopamine transporter gene VNTR polymorphism | en |
| dc.type | info:eu-repo/semantics/article | et |
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CoCA — Aktiivsus-tähelepanuhäirega koosesinevad haigused ja tervisehäired / Comorbid Conditions of Attention Deficit/Hyperactive Disorders
Eat2beNICE — Toitumise ja eluviisi mõju impulsiivsele, kompulsiivsele ja eksternaliseeritud käitumisele / Effects of Nutrition and Lifestyle on Impulsive, Compulsive, and Externalizing Behaviours
Eat2beNICE — Toitumise ja eluviisi mõju impulsiivsele, kompulsiivsele ja eksternaliseeritud käitumisele / Effects of Nutrition and Lifestyle on Impulsive, Compulsive, and Externalizing Behaviours