The role of β-integrin myospheroid in the wing development of Drosophila melanogaster

Abstract

Integrins are family of transmembrane cell adhesion receptors that are very important organism development. Integrins are responsible for many cellular function including proliferation, migration, polarisation, apoptosis and differentiation. Integrins are composed from two subunits α and β. To study the spatiotemporal importance of β-integrin to wing phenotype of Drosophila melanogaster, UAS/GAL4 system under control of thermosensitive GAL80 system was used was used in this thesis.