Sample size calculations in clinical trials
Date
2016
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Abstract
The aim of this thesis is to give an overview of calculating sample size in clinical trials. First, a brief introduction to clinical trials and factors affecting sample size is given. This is followed by chapters on sample size calculations for three main trial types. Every design is then illustrated by a practical example and instructions for calculations in SAS and R software.
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Keywords
clinical trials, R, sample size, SAS, kliinilised uuringud, valimimaht